Table 3.
Association between BMI status before HCC diagnosis and age at onset of HCC (Multiple Linear Regression)
| Age (Range) | Patients (N) | Age at HCC onset (years) | Mean difference (95% CI) | P Value | |
|---|---|---|---|---|---|
| Median (IQR) | Mean (±SD) | ||||
| Mid-20s | |||||
| Normal weight | 438 | 70 (62–79) | 63.4 (±11.19) | ||
| Overweight | 135 | 62 (56–70) | 63.0 (±10.6) | −2.0 (−4.1 to .06) | .057 |
| Obese | 46 | 61 (55–70) | 60.1 (±11.6) | −4.1 (−7.2 to .85) | .013 |
| Mid-30s | |||||
| Normal weight | 356 | 63 (56–72) | 63.7 (±11.3) | ||
| Overweight | 191 | 64 (56–70) | 63.2 (±10.5) | −1.6 (−3.5 to 21) | .084 |
| Obese | 73 | 60 (55–69) | 61.3 (±10.2) | −5.1 (−7.7 to 2.4) | <.001 |
| Mid-40s | |||||
| Normal weight | 281 | 65 (56–73) | 64.3 (±11.9) | ||
| Overweight | 203 | 64 (57–71) | 64.3 (±9.1) | −.5 (−2.3 to 1.3) | .589 |
| Obese | 127 | 60 (56–68) | 61.7 (±9.1) | −4.14 (−6.2 to 2.1) | <.001 |
| Mid-50s | |||||
| Normal weight | 217 | 64 (56–74) | 64.7 (±12.3) | .9 (−.8 to 2.7) | .3 |
| Overweight | 205 | 66 (60–72) | 66.5 (± 8.5) | −1.7 (−3.8 to .3) | .09 |
| Obese | 134 | 63 (59–69) | 64.3 (±6.9) | ||
Abbreviations: BMI, body mass index; CI, confidence interval; HCC, hepatocellular carcinoma; IQR, interquartile range