Figure 3. Induction of LP CD4+LAP+ cells by CD11c DCs in vitro.

A. Percentages of LAP+ cells in purified lamina propria CD4+ T cell populations following co-culture for 48 hrs. with CD11c+ DCs isolated from the lamina propria of Nod2−/− and Nod2+/+ mice. Column represent mean±SE of data from two different experiments. B. Percentages of LAP+ cells in purified lamina propria CD4+ T cell populations following co-culture for 48 h. with CD11c+ DCs isolated from the lamina propria of Nod2−/− and Nod2+/+ mice in the presence or in the absence of Pam3CSK4. Column represent mean±SE of data from two different experiments.