Figure 1. The effect of ADRB1 haplotype on treatment response in patients with hypertension.
The Ser49/Arg389 haplotype is associated with a significantly increased risk of death in patients treated with a verapamil-based strategy. This increased risk is offset by treatment with an atenolol-based treatment strategy. AT, atenolol; VE, verapamil SR. Permission obtained from Wiley Ltd © Pacanowski, M. A. et al. Clin. Pharmacol. Ther. 84, 715–721 (2008).