Fig 6. Age-dependent spatial reference learning and memory impairments of 5xFAD mice.

5xFAD mice demonstrated impaired learning ability to locate the hidden platform in an age-dependent manner (A). *P<0.05 vs other groups. (B) 5xFAD mice had compromised function in spatial reference memory in an age-dependent manner. *P<0.05 vs other groups. (C) Mice in different groups didn't show significant change in their swimming speed. N = 5–6 mice of each group.