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. 2016 Mar 4;11(3):e0151005. doi: 10.1371/journal.pone.0151005

Table 1. Variations in mean arterial pressure and heart rate throughout the experiment in all groups.

Mean Arterial Pressure (mmHg)
Groups t0—Baseline t1–2 h post-LPS t2 –post-HSA t3–1 h post-HSA
SHAM 126 [95–142] 118 [84–137] 123 [88–136] 134 [101–149]
LPS 131 [107–136] 113 [76–138] 121 [53–148] -
LPS+0.9%NaCl 121 [95–134] 114 [61–140] 100 [71–131] -
LPS+4%HSA 124 [110–138] 110 [82–140] 89 [82–129] 77 [40–135]
LPS+20%HSA 118 [101–127] 110 [83–114] 88 [78–118] 71 [58–85]
Heart Rate (bpm)
Groups t0—Baseline t1–2 h post-LPS t2 –post-HSA t3–1 h post-HSA
SHAM 293 [236–309] 280 [259–335] 287 [249–320] 276 [259–332]
LPS 296 [240–354] 295 [251–299] 286 [249–305] -
LPS+0.9%NaCl 346 [316–371] 300 [260–334] 350 [293–396] -
LPS+4%HSA 306 [285–365] 340 [308–365] 397 [355–407]*##aa 365 [305–404]
LPS+20%HSA 281 [217–342] 320 [284–343] 322 [274–354] 257 [228–315]

Six animals per group were studied. One rat in the LPS group died after t1, leaving 5 animals in this group at t2 (post HSA). Data are expressed as the median [interquartile range]. LPS lipopolysaccharide; HSA Human Serum Albumin.

*p<0.05, versus LPS;

## p<0.01, versus LPS+0.9%NaCl;

aa p<0.01, versus t0-Baseline.