Table 2.
Demographic Parameter | MS n=113 |
Asymptomatic n=1583 |
p-value |
p-value Adjusted * |
---|---|---|---|---|
Age at enrollment: year, Mean (SD) 1 | 39.2 (7.5) | 33.8 (8.5) | <0.0001 | N/A |
European descent, non-Hispanic: n (%) | 103 (95%) | 1458 (96%) | 0.86 | N/A |
Female: n (%) | 96 (85%) 2 | 1248 (79%) | 0.12 | 0.14 |
Smoking, current: n (%) | 16 (14%) | 122 (8%) | 0.015 | 0.01 |
IM: n (%) | 31 (27%) | 394 (25%) | 0.55 | 0.39 |
% first-degree relatives with MS: Mean (SD) | 23% (12%) | 26% (12%) | 0.25 | N/A |
BMI at age 18: Mean (SD) | 23.1 (5.3) | 22.7 (4.2) | 0.39 | N/A |
Abbreviation: IM, history of infectious mononucleosis; % first-degree relatives with MS: percentage of a subject's total number of first-degree relatives with MS; BMI, body mass index; N/A: not applicable.
Adjusted for age since MS subjects in the GEMS study have a higher mean age at enrollment than asymptomatic subjects.
Note 1: Age at GEMS study enrollment is not the same as the age at MS diagnosis.
Note 2: Among the GEMS subjects with MS, the female to male ratio is 5.6 to 1.