Fig. 3.

KLH- and prophylactic vaccine-specific T cell responses before and after VAC-DC vaccination. a KLH-specific T cell proliferation was analyzed before the first vaccination and after each VAC-DC vaccination during the first vaccination cycle in PBMC. Per time point each dots represents one patient; black dots represent patients that received i.v./i.d. VAC-DC vaccination, open dots represent patients that received i.n. VAC-DC vaccination. Horizontal lines represent group averages per time point. In all patients except one, a KLH-specific T cell response was induced. b BCG-, Act-HIB-, and Typhim-specific T cell proliferation was analyzed before and after VAC-DC vaccination in PBMC. Proliferative responses to KLH or prophylactic vaccines are given as proliferation index (proliferation with KLH or vaccines/proliferation without KLH or vaccines). **p < 0.01, paired t test