Figure 4. Substrate and activity-based probes.
(ABPs) A. The cathespin targeted covalent probe BMV109 B. The cathepsin targeted substrate LUM015 C. The polyer-based protease substrate probe C-PGC probe D. A polymer MMP-2-sensitive NIRF substrate E. The turn-on fluorophore based probe for cathepsins, Z-Phe-Arg-HMRG.