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. 2016 Mar 5;17:17. doi: 10.1186/s12881-016-0279-1

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© Janssen et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Placental PHLDA2 expression in RFM pregnancies. Placental PHLDA2 expression was significantly increased in RFM pregnancies resulting in delivery of a growth restricted infant (a) Fetal growth restriction was defined as delivery of a term infant with a custom birth weight centile <10^th. Placental PHLDA2 was not significantly altered in RFM pregnancies where infants were born preterm (b) or admitted to NICU at delivery (c) There was a significant inverse association between placental PHLDA2 expression and maternal serum hPL levels (d) RFM = reduced fetal movements. Error bars represent SEM. ** P < 0.01