Fig. 2.

Number of thrombotic/thromboembolic (a) and major bleeding events (b) in MPN over time in months. The 0 (zero) marks the date of diagnosis. In a (thrombotic and thromboembolic events), there are several events before and after diagnosis which presents almost like a normal distribution. While in b (bleedings events), there were only two cases of major bleedings described before date of diagnosis—all other major bleedings occurred after that date