Table 2.
Thrombosis/thromboembolism and bleeding events in MPN
| All Pts | PV | ET | PMF | Post-PV-MF | Post-ET-MF | MPN-U | p value# | |
|---|---|---|---|---|---|---|---|---|
| Thrombosis/thromboembolisma; n (%) | 147 (33.6) n = 438 |
54 (38.9) n = 139 |
33 (25) n = 132 |
34 (31.2) n = 109 |
13 (61.9) n = 21 |
8 (42.1) n = 19 |
5 (27.8) n = 18 |
0.0120 |
| DVT; n (%) | 46 (31.5) n = 146 |
15 (27.8) n = 54 |
10 (30.3) n = 33 |
11 (33.3) n = 33 |
4 (30.8) n = 13 |
3 (37.5) n = 8 |
3 (60) n = 5 |
0.7781 |
| ACS; n (%) | 41 (27.7) n = 148 |
15 (27.8) n = 54 |
12 (35.3) n = 34 |
7 (20.6) n = 34 |
4 (30.8) n = 13 |
2 (25) n = 8 |
1 (20) n = 5 |
0.8439 |
| Stroke; n (%) | 28 (19.3) n = 145 |
13 (24.5) n = 53 |
7 (21.2) n = 33 |
7 (21.2) n = 33 |
0 (0) n = 13 |
0 (0) n = 8 |
1 (20) n = 5 |
0.2714 |
| SVT; n (%) | 22 (15.2) n = 145 |
3 (5.7) n = 53 |
6 (18.2) n = 33 |
6 (18.2) n = 33 |
4 (30.8) n = 13 |
0 (0) n = 8 |
3 (60) n = 5 |
0.0083 |
| Bleedinga, n (%) | 36 (8.2) n = 437 |
13 (9.4) n = 139 |
5 (3.8) n = 133 |
10 (9.3) n = 108 |
4 (19.1) n = 21 |
1 (5.3) n = 19 |
3 (17.7) n = 17 |
0.0586 |
| Upper GI-Tract-Bleeding; n (%) | 20 (55.6) n = 36 |
7 (53.9) n = 13 |
3 (69) n = 5 |
6 (60) n = 10 |
3 (75) n = 4 |
0 (0) n = 1 |
1 (33.3) n = 3 |
0.8748 |
| Postinterventional; n (%) | 4 (11.1) n = 36 |
3 (23.1) n = 13 |
0 (0) n = 5 |
0 (0) n = 10 |
0 (0) n = 4 |
1 (100) n = 1 |
0 (0) n = 3 |
0.0958 |
| CNS; n (%) | 3 (8.3) n = 36 |
0 (0) n = 13 |
0 (0) n = 5 |
3 (30) n = 10 |
0 (0) n = 4 |
0 (0) n = 1 |
0 (0) n = 3 |
0.1725 |
Pts patients, DVT deep vein thrombosis, ACS acute coronary syndrome, SVT splanchnic vein thrombosis, CNS central nervous system
#In Fisher’s exact test
aLife-time events