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. 2016 Mar 1;33(5):425–438. doi: 10.1089/neu.2014.3812

Table 1.

Inclusion and Exclusion Criteria Used in the Present Study

  Inclusion criteria Exclusion criteria
Population and condition Adult human participants (19–70 years, sample size >5 participants) with a history of traumatic SCI: acute/subacute (defined as within min to 12 months post-injury) and/or chronic (after 12 months post-injury). Studies exclusively in adolescents and children (age <19 years old); Case studies/case series (defined as having a sample size <5 participants); studies performed in animal models or experimental models of SCI; studies including individuals with nontraumatic SCI; studies with participants who have other neurologic, cognitive or orthopedic conditions associated with the SCI (metastatic cancer, etc).
Interventions Cell therapies, pharmacology approaches, electrical stimulation/neuroelectric devices, rehabilitation or a combination of therapies including any of the above strategies. Studies that: were not designed to assess the effects of an intervention (observational studies, studies carried out to assess an outcome measure); did not include a performance-based measure of motor function; assessed gangliosides and methylprednilosone, surgical decompression of the spinal cord, or were not available in full text.
Comparisons of interest Intervention vs. active or inactive control; pre-intervention/post-intervention (for studies that did not include a control group). None
Study design Studies with an active control group (comparison group) were preferred, but studies with inactive controls (placebo or wait-list control), and safety/feasibility studies were also included. Observational studies; studies carried out using retrospective analysis of clinical findings and studies with no original data (reviews)
Timing/setting Longitudinal studies that occur in general and clinical settings. None

SCI, spinal cord injury.