Table 2.

Mean±SD together with the independent t-test for unsaturated fatty acid composition of brain tissue (Pg/ml) between neurointoxicated, protected, and therapeutically treated rat pups compared to healthy control.

Unsaturated fatty acids	Control	PA	Melatonin+PA	PA+Melatonin	CoQ+PA	PA+CoQ
α-Linolenic	0.41±0.07	0.31±0.02	0.31±0.03	0.37±0.02	0.42±0.03	0.46±0.03
		0.004	0.002	ns	ns	ns
Stearidonic	0.20±0.04	0.45±0.04	0.41±0.04	0.38±0.03	0.40±0.03	0.46±0.04
		0.001	0.001	0.001	0.001	0.001
Linoleic	0.29±0.05	0.47±0.04	0.52±0.05	0.57±0.05	0.57±0.11	0.63±0.09
		0.001	0.001	0.001	0.001	0.001
γ-Linolenic	0.43±0.06	0.14±0.01	0.17±0.02	0.18±0.01	0.22±0.02	0.24±0.04
		0.001	0.001	0.001	0.001	0.001
Oleic	0.74±0.09	0.62±0.04	0.57±0.05	0.52±0.03	0.51±0.05	0.50±0.05
		0.004	0.001	0.001	0.001	0.001
Eicosapentaenoic	0.43±0.04	0.37±0.03	0.42±0.03	0.32±0.03	0.38±0.04	0.39±0.05
		0.006	ns	0.001	0.031	ns
Arachidonic	0.38±0.04	0.31±0.03	0.43±0.04	0.37±0.04	0.38±0.04	0.42±0.03
		0.001	ns	ns	ns	ns
Docosahexaenoic	0.64±0.07	0.53±0.05	0.64±0.06	0.51±0.04	0.52±0.08	0.54±0.09
		0.001	ns	0.001	0.006	0.029