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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Diabetologia. 2016 Jan 13;59(4):734–743. doi: 10.1007/s00125-015-3859-2

Fig. 2.

Fig. 2

Effects of adult beta cell-specific Bmal1 deletion on fasting and diurnal glycaemia in vivo following exposure to either chow or HFD. Graphs representing longitudinal changes in fasting glucose in different β-Bmal1 mice at baseline (time-0), and 2, 4, 6 and 8 weeks after tamox-ifen in mice fed (a) chow or (b) HFD. (a, b) Each data point represents mean ± SEM (n=5–7 per group per time point). Statistical significance is denoted by *p<0.05 compared with own baseline. Inserts represent mean fasting glucose in respective genotypes at week 8. Bar graphs representing diurnal plasma glucose under ad libitum fed conditions following 8-week exposure to (c) chow or (d) HFD. (c, d) Graphs represent mean ± SEM (n=5–7 per group). Statistical significance is denoted by *p<0.05 and **p<0.01. (a–d) β-Bmal1+/+, white circles/bars; β-Bmal1+/−, grey circles/bars; β-Bmal1−/−, black circles/bars