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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Brain Behav Immun. 2015 Sep 5;55:6–16. doi: 10.1016/j.bbi.2015.09.001

Figure 6. Systemic microglia depletion via administration of PLX3397 may lead to temporary alterations in spatial memory.

Figure 6

(A) Barnes maze test was conducted for 5 consecutive days 21 days after administration of PLX3397. The time taken by the mice to find the escape box is shown. n=5–7 per group. Data are shown as mean ± SEM. ** p<0.01 (B–C) The locomotor activity of the mice was assessed using the open field activity test on the last day of Barnes maze testing. n=5–7 per group. (D). Lower and upper limb strength was measured in the Rotorod on the last day of Barnes maze testing. n=5–7 per group. Data are shown as mean ± SEM.