Skip to main content
. Author manuscript; available in PMC: 2017 Mar 15.
Published in final edited form as: J Neurol Sci. 2015 Dec 28;362:131–135. doi: 10.1016/j.jns.2015.12.038

Figure 4.

Figure 4

(A) Bortezomib dose response curve plotted as log of concentration. Different rodent strains had different responses to bortezomib. DBA/2J and C3H/HeJ DRG-NOG had biphasic dose response curves while rat, C57BL/6J and Balb/cJ dose response consistently decreased. Comparison of rat and mouse DRG-NOG at (B) 50 nM bortezomib treatment showed DBA/2J and C3HHE/J mouse DRG are less sensitive to bortezomib than rat, C57BL6/J and Balb/cJ DRG-NOG. (p<0.01-p<0.0001).