Fig. 2.—

Genetic organization of ESX loci. (A) Genetic organization of ESX-P loci in mycobacterial plasmids. ESX-P clusters 2–4 represent new ESX types found in more than one plasmid. (B) Genetic organization of chromosomal ESX loci from a representative mycobacterial data set together with Nocardia farcinica and Gordonia bronchialis strains. Note that within the ESX-1 locus, the downstream gene of esxA was drawn according to the highest coding probability scores, which for Mycobacterium tuberculosis and Mycobacterium marinum were different from the original annotation.