Fig. 4.—
ESX loci within synteny blocks. Purple arrows: genes involved in synteny block within contiguous region of ESX loci. (A) Synteny blocks involving ESX loci of mycobacterial plasmids from each ESX-P plasmid cluster and Mycobacterium gilvum pMFLV01. (B) Synteny blocks within Mycobacterium sinense JDM601 ESX-2 genomic region. Upper panel: genetic organization of ESX plasmids pMYCCH02 and pMKMS02 in synteny with M. sinense JDM601 ESX-2 locus. Lower panel: a representative subset of SGM and RGM, respectively, and other closely related actinobacteria were investigated. Blue boxes: synteny blocks. Surrounding purple box: plasmid.