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. 2016 Jan 8;8(2):387–402. doi: 10.1093/gbe/evw001

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© The Author(s) 2016. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Fig. 5.— — SGM-specific genes of Mycobacterium tuberculosis H37Rv and ESX-5 genomic organization. (A) SGM-specific genes involved in mobility regions. First inner circle: GC%. Second inner circle: red boxes represent M. tuberculosis genes with homologs in Mycobacterium avium and Mycobacterium sinense JDM501 but without any homolog in Mycobacterium smegmatis, Mycobacterium gilvum PYR-GCK, or Mycobacterium abscessus (BBH 30% identity) and identified within synteny groups containing composition bias according to Alien Hunter software. Third inner circle: purple boxes represent ESX loci. First outer circle: tRNAs. Secound outer circle: insertion sequences. (B) Synteny blocks within ESX-5 region of M. tuberculosis H37Rv. A representative subset of SGM and RGM, respectively, and other closely related actinobacteria were investigated. MTC, Mycobacterium terrae complex. Blue boxes: synteny blocks. Purple box: ESX-5 locus.