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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Brain Res. 2015 Dec 28;1634:119–131. doi: 10.1016/j.brainres.2015.12.048

Figure 1. Tau facilitates KA-induced seizures in vivo.

Figure 1

WT (n = 5) and tau−/− (n = 6) mice received 25mg/kg KA (i.p.) prior to 1 hour of video recording of seizure behavior. Seizure severity was determined based on a modified Racine scale. Seizure scores were binned by 5 min for each animal and data are presented as the averages of binned seizure severity scores +/− SEM (A). The graph in (B) represents the percent of WT and tau−/− mice that reached each level of seizure severity over the hour observation period. (** indicates P<0.05; *** indicates P<0.001)