Table 1.
BAFF and CD40-responsive genes controlled by the alternative NF-κB pathway as identified by RNA-seq analysis of BAFF and CD40-stimulated nfkb2-deleted and WT B-cells.
| 6h BAFF | 6h CD40 | ||||
|---|---|---|---|---|---|
| Functional category | Gene | Fold change | padj value | Fold change | padj value |
| - | Nfkb2 | −2.53 | 3.72E-88 | −3.23 | 0 |
| IMMUNE RESPONSE – B CELL | Fcer2a (CD23) | −1.33 | 0.018 | −1.39 | 7.03E-58 |
| APOPTOSIS | Bcl2 | −1.33 | 0.029 | unchanged | - |
| TRAFFICKING | Sell | −1.47 | 1.49E-15 | unchanged | - |
| Gpr183 (Ebi2) | −1.49 | 1.27E-12 | −1.35 | 2.05E-20 | |
| Ccr7 | −1.61 | 3.95E-10 | −1.22 | 1.71E-12 | |
| Cxcr5 | −1.19 | 0.0099 | unchanged | - | |
| IMMUNE RESPONSE – T-DEPENDENT | H2-DMb2 | −1.32 | 8.73E-07 | unchanged | - |
| Icosl | −1.28 | 5.89E-06 | unchanged | - | |
| Ctss | −1.27 | 0.00013 | unchanged | - | |
| H2-Oa | −1.25 | 0.0038 | unchanged | - | |
| Cd83 | −1.92 | 0.0083 | unchanged | - | |
| H2-Aa | −1.28 | 0.014 | unchanged | - | |