Skip to main content
. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Pharmacol Ther. 2016 Jan 22;159:83–92. doi: 10.1016/j.pharmthera.2016.01.006

Fig. 3.

Fig. 3

Human melanoma cells were cultured in 3-dimensional Matrigel matrices without (Control) or with 1, 10 and 50 nM CVM-1118. After 24 hr, four images per treatment were digitally captured and representative images shown here. These images were then converted to binary images (as shown) and analyzed using the Angiosys software to determine the average number of junctions and average total tubule length per field for the four images per parameter. Statistically significant changes (p<0.05) are marked with an * in the bar graphs. (Magnification 100×; scale bar = 100 μm.)