Table 3.
Ocular Examination Findings of the Study Population
| Eyelid Laxity (any upper or lower) |
No Eyelid Laxity |
p value | ||
|---|---|---|---|---|
| Conjunctivochalasis (n, %) | nasal | 40 (44%) | 6 (16%) | <0.005 |
| non-nasal | 39 (43%) | 16 (42%) | ||
| none | 11 (12%) | 16 (42%) | ||
| Osmolarity (mOsm/L) | 303.9±16 | 309±22 | 0.13 | |
| TBUT (seconds) (mean±SD) | 8.6±3 | 10.3±4 | 0.02 | |
| Corneal staining (mean±SD) | 2.5±3 | 1±2 | 0.002 | |
| Corneal staining ≥2 (n, %) | 52 (53%) | 9 (23%) | 0.001 | |
| Schirmer's score (mm) (mean±SD) | 14±6 | 17±7 | 0.01 | |
| Meibomian gland drop out (mean±SD) | 1.9±0.99 | 0.8±0.8 | <0.005 | |
| Meibomian gland drop out ≥2 (n, %) | 63 (64%) | 4 (10%) | <0.005 | |
| Eyelid vascularity (mean±SD) | 0.8±0.8 | 0.2±0.5 | <0.005 | |
| Eyelid vascularity ≥2 (n, %) | 23 (24%) | 1 (3%) | 0.003 | |
| Meibum quality (mean±SD) | 2±1.3 | 1.4±1.2 | 0.022 | |
| Meibum quality ≥2 (n, %) | 55 (61%) | 18 (49%) | 0.120 |
Tear break-up time (TBUT)
*
All ocular examination findings reflect the value of the more severely affected eye.