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. Author manuscript; available in PMC: 2017 Mar 15.
Published in final edited form as: J Immunol. 2016 Feb 12;196(6):2450–2455. doi: 10.4049/jimmunol.1502525

Figure 2. Decreased Tcm generation by RTE-derived memory T cells.

Figure 2

5x103 each of OT-I TCR Tg RTEs and MN T cells were co-transferred into congenic hosts that were infected the following day with Lm.OVA. A) Splenocytes were analyzed on d60 post-infection. Shown are the percent of RTE and mature CD8+ T cells expressing CD62L and Eomes directly ex vivo and IL-2 production after peptide restimulation. Data are presented as mean ± SEM and are compiled from 2–4 independent experiments. B) Blood was analyzed at the same time points as in Figure 1A to determine the percent of RTE-derived and mature T cells that were CD62Lhi. Data are presented as mean ± SEM and are compiled from 4 independent transfers; n=6–21. * p values vary from <0.05 to < 0.0001 by paired Student’s t test.