Table 2.
Baseline and Final Hemodynamics of the Study Population*
| Variable | Preserved Cardiac Index (≥2 L/min/m2) | Reduced Cardiac Index (<2 L/min/m2) | p | ||
|---|---|---|---|---|---|
| PCWP < 20 (N=74) | PCWP ≥ 20 (N=37) | PCWP < 20 (N=23) | PCWP ≥ 20 (N=17) | ||
| Baseline Hemodynamics | |||||
| RAP, mmHg | 10 (6 – 15) | 12 (8 – 20) | 13 (8 – 18) | 17 (12.5 – 20) | 0.01 |
| PA mean, mmHg | 33 (26 – 41) | 39 (33 – 46) | 34.5 (32 – 44) | 45 (31.5 – 49) | 0.04 |
| CI, L/min/m2 | 2.0 (1.8 – 2.4) | 2.1 (1.7 – 2.4) | 1.5 (1.2 – 1.8) | 1.6 (1.4 – 1.9) | <0.001 |
| CO, L/min | 3.9 (3.1 – 4.7) | 4 (3.6 – 5.1) | 2.9 (2.4 – 3.2) | 3.23 (2.7 – 4.0) | <0.001 |
| SVR, dynes x sec/cm2 | 1322 (1116–1631) | 1162 (921–1440) | 1923 (1350–2088) | 1546 (1464–2003) | <0.001 |
| PCWP, mmHg | 22 (16 – 27) | 25 (21 – 36) | 25.5 (20 – 30) | 28.5 (24 – 33.5) | <0.001 |
| Final Hemodynamics | |||||
| RAP, mmHg | 6 (4 – 10) | 11 (9 – 15) | 5 (4 – 8) | 12 (9 – 20) | <0.001 |
| PA mean, mmHg | 25.5 (22 – 30) | 33.5 (30 – 39) | 23 (20 – 32) | 38 (33 – 40) | <0.001 |
| CI, L/min/m2 | 2.6 (2.2 – 2.8) | 2.5 (2.3 – 2.9) | 1.73 (1.5 – 1.9) | 1.60 (1.5 – 1.9) | by definition |
| CO, L/min | 4.81 (4.3 – 5.6) | 5.10 (4.58 – 5.9) | 3.18 (2.61 – 3.6) | 3.3 (2.8 – 3.9) | <0.001 |
| SVR, dynes x sec/cm2 | 1083 (813 – 1207) | 867 (568 – 1022) | 1735 (1490–1903) | 1446 (1213–1748) | <0.001 |
| PCWP, mmHg | 14 (10 – 17) | 22 (21 – 24) | 13 (11 – 15) | 26 (23 – 30) | by definition |
*
Presented as median (25th, 75th percentile).
Abbreviations: CI: cardiac index, CO: cardiac output, PA: pulmonary artery, PCWP: pulmonary capillary wedge pressure, RAP: right atrial pressure, SVR: systemic venous resistance