| Acini |
Similar to normal acini |
Prominent atypia |
| Growth pattern |
Well-circumscribed, lobular, usually merge with atrophic glands |
Diffused and disordered, distinct from adjacent benign glands |
| Cytoplasm |
Pale and clear, apical cytoplasm typically lost with preservation of lateral cytoplasm |
Amphophilic, apical cytoplasm typically preserved or increased while lateral is lost |
| Nuclei |
Separating, bland |
Crowding, large and atypical |
| Nucleolus |
Small and inconspicuous |
Large and prominent |
| Basal cell |
Small and inconspicuous + may discontinuous and focal |
|
| Laminated corpora amylacea |
Common |
Rare |
| Blue-tinged mucin |
Rare |
Common |
