Table 1.
Patient demographic and clinical characteristics.
| S group (n = 78) |
C group (n = 96) |
P | |
|---|---|---|---|
| Sex (M/F) | 26/52 | 41/55 | 0.215 |
| Age (years) | 76 ± 7 | 75 ± 9 | 0.240 |
| BMI (kg/m2) | 22 ± 4 | 23 ± 3 | 0.738 |
| Smoking Hx (pack-year) | 3 ± 11 | 3 ± 10 | 0.903 |
| Underlying disease | |||
| Hypertension | 56 | 59 | 0.198 |
| DM | 24 | 24 | 0.495 |
| Dyslipidemia | 21 | 23 | 0.727 |
| Angina pectoris | 9 | 13 | 0.820 |
| Current medications | |||
| Alpha-blocker | 0 | 2 | 0.502 |
| ARB | 23 | 26 | 0.738 |
| ACEi | 2 | 2 | 1.000 |
| Beta-blocker | 15 | 13 | 0.407 |
| CCB | 30 | 30 | 0.340 |
| Statin | 12 | 23 | 0.186 |
| LVEF (%) | 67.5 ± 9.9 | 69.0 ± 6.3 | 0.334 |
| PFT | |||
| FEV1 (L) | 1.7 ± 0.6 | 1.7 ± 0.5 | 0.598 |
| FVC (L) | 2.3 ± 0.9 | 2.5 ± 0.8 | 0.166 |
| FEF 25–75% (L/s) | 1.4 ± 0.7 | 1.3 ± 0.7 | 0.868 |
| Operation | 0.215 | ||
| CR and IF | 34 | 34 | |
| OR and IF | 7 | 14 | |
| Bipolar | 12 | 24 | |
| THR | 25 | 24 | |
| Anesthesia time (min) | 178 ± 46 | 186 ± 74 | 0.401 |
| Operation time (min) | 126 ± 48 | 122 ± 68 | 0.648 |
| pRBC transfusion (unit) | 1.4 ± 1.5 | 1.6 ± 2.4 | 0.510 |
| Postop. bleeding (mL) | 230 ± 292 | 298 ± 329 | 0.156 |
| Postop. VAS1 | 39 ± 18 | 43 ± 14 | 0.124 |
| Postop. VAS2 | 31 ± 11 | 32 ± 9 | 0.567 |
Data are numbers of patients or mean ± standard deviation.
S group, sugammadex group; C group, conventional cholinesterase inhibitor group; M, male; F, female; DM, diabetes mellitus; CVA, cerebrovascular accident; ARB, angiotensin receptor blocker; ACEi, angiotensin converting enzyme inhibitor; CCB, calcium channel blocker; NTG, nitroglycerin; LVEF, left ventricular ejection fraction before operation; PFT, pulmonary function test before operation; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; FEF 25–75%, forced expiratory flow rate at 25–75%; Op, operation; CR and IF, closed reduction and internal fixation; bipolar, bipolar hemiarthroplasty; THR, total hip replacement; anesthesia time, time from arrival at operation room to discharge from the operating room; Op time, time from skin incision to dressing; pRBC, packed red blood cells; postop. bleeding, postoperative bleeding up to 24 hours postoperatively; postop. VAS1, postoperative visual analogue scale score at discharge from the postanesthesia care unit; postop. VAS2, postoperative visual analogue scale score on postoperative day 1.