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Skin measurements by biophysical evaluation methods were taken at baseline, 1 week, 4 weeks, and 12 weeks after treatment on both sides. (a) Objective measurement of erythema index, (b) melanin index, (c) overall elasticity (R2), (d) hydration, (e) glossy, and (f) TEWL. ∗ P < 0.05 compared with control side at same time point; # P < 0.05 compared with baseline.
