Table 1. Baseline characteristics of 247 patients included in analyses at the start of ART.
| Characteristics | No (%) of patients by visit constancy | P value | |||
|---|---|---|---|---|---|
| Total (n = 247) |
100% (n = 166) |
51-99% (n = 48) |
≤ 50% (n = 33) |
||
| Sex | 0.597 | ||||
| Male | 212 (85.8) | 142 (85.5) | 43 (89.6) | 27 (81.8) | |
| Female | 35 (14.2) | 24 (14.5) | 5 (10.4) | 6 (18.2) | |
| Age at ART start, median (IQR), yr | 42 (36-50) | 44 (38-51) | 40 (33-47) | 38 (31-49) | 0.006 |
| > 50 | 63 (25.5) | 47 (28.3) | 9 (18.8) | 7 (21.2) | 0.014 |
| 41-50 | 88 (35.6) | 66 (39.8) | 13 (27.1) | 9 (27.3) | |
| 31-40 | 69 (27.9) | 43 (25.9) | 16 (33.3) | 10 (30.3) | |
| ≤ 30 | 27 (10.9) | 10 (6.0) | 10 (20.8) | 7 (21.2) | |
| Route of transmission | 0.095 | ||||
| Heterosexual | 134 (54.3) | 92 (55.4) | 20 (41.7) | 22 (66.7) | |
| Homo/bisexual | 108 (43.7) | 70 (42.2) | 28 (58.3) | 10 (30.3) | |
| IDU/transfusion | 5 (2.0) | 4 (2.4) | 0 (0) | 1 (3.0) | |
| Marriage | 0.185 | ||||
| Unmarried | 102 (41.3) | 61 (36.7) | 24 (50.0) | 17 (51.5) | |
| Married | 92 (37.2) | 70 (42.2) | 14 (29.2) | 8 (24.2) | |
| Divorced/separated by death | 53 (21.5) | 35 (21.1) | 10 (20.8) | 8 (24.2) | |
| Health security system | 0.345 | ||||
| Health insurance | 168 (68.0) | 114 (68.7) | 29 (60.4) | 25 (75.8) | |
| Medical aid | 79 (32.0) | 52 (31.3) | 19 (39.6) | 8 (24.2) | |
| Residential area | 0.485 | ||||
| Busan | 180 (72.9) | 122 (73.5) | 31 (64.6) | 27 (81.8) | |
| Surrounding satellite city | 44 (17.8) | 30 (18.1) | 10 (20.8) | 4 (12.1) | |
| Other city or region | 23 (9.3) | 14 (8.4) | 7 (14.6) | 2 (6.1) | |
| Non-HIV related comorbidity (Charlson comorbidity index)* | 0.039 | ||||
| 0 | 165 (66.8) | 104 (62.7) | 33 (68.8) | 28 (84.8) | |
| ≥ 1 | 82 (33.2) | 62 (37.3) | 15 (31.3) | 5 (15.2) | |
| Psychiatry disorder | 0.875 | ||||
| No | 228 (92.3) | 153 (92.2) | 45 (93.8) | 30 (90.9) | |
| Yes | 19 (7.7) | 13 (7.8) | 3 (6.3) | 3 (9.1) | |
| History of substance abuse | 0.801 | ||||
| No | 242 (98.0) | 163 (67.4) | 47 (19.4) | 32 (13.2) | |
| Yes | 5 (2.0) | 3 (60.0) | 1 (20.0) | 1 (20.0) | |
| CD4 cell counts on ART initiation, median (IQR), cells/µL | 130 (44.0-249.0) | 118 (37.8-227.8) | 109.5 (39.3-249.8) | 229 (77.0-326.0) | 0.012 |
| ≤ 200 | 158 (64.0) | 114 (68.7) | 29 (60.4) | 15 (45.5) | 0.075 |
| 201-300 | 54 (21.9) | 32 (19.3) | 13 (27.1) | 9 (27.3) | |
| > 300 | 35 (14.2) | 20 (12.0) | 6 (12.5) | 9 (27.3) | |
| Clinical category at ART start | 0.080 | ||||
| A | 124 (50.2) | 82 (49.4) | 22 (45.8) | 20 (60.6) | |
| B | 46 (18.6) | 30 (18.1) | 7 (14.6) | 9 (27.3) | |
| C | 77 (31.2) | 54 (32.5) | 19 (39.6) | 4 (12.1) | |
| Duration from HIV diagnosis to ART initiation, yr | 0.36 (0.15-2.65) | 0.28 (0.12-1.49) | 1.31 (0.24-5.11) | 0.42 (0.2-3.21) | 0.002 |
| < 1 | 160 (64.8) | 119 (71.7) | 23 (47.9) | 18 (54.5) | 0.014 |
| 1-5 | 48 (19.4) | 25 (15.1) | 13 (27.1) | 10 (30.3) | |
| > 5 | 39 (15.8) | 22 (13.3) | 12 (25.0) | 5 (15.2) | |
| First ART | 0.463 | ||||
| Unboosted PIs | 59 (23.9) | 37 (22.3) | 10 (20.8) | 12 (36.4) | |
| Boosted PIs | 111 (44.9) | 75 (45.2) | 22 (45.8) | 14 (42.4) | |
| NNRTI | 77 (31.2) | 54 (32.5) | 16 (33.3) | 7 (21.2) | |
| ART regimen during the 5 yr after ART initiation | 0.080 | ||||
| PIs | 124 (50.2) | 82 (49.4) | 22 (45.8) | 20 (60.6) | |
| NNRTIs | 46 (18.6) | 30 (18.1) | 7 (14.6) | 9 (27.3) | |
| Mixed | 77 (31.2) | 54 (32.5) | 19 (39.6) | 4 (12.1) | |
Data are number (%) of patients, unless otherwise indicated. *Excluding AIDS as a co-morbidity. HIV, human immunodeficiency virus; IQR, interquartile range; ART, anti-retroviral therapy; IDU, injection drug user; PI, protease inhibitor; NNRTI, non-nucleotide reverse transcriptase inhibitor.