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. 2016 Mar 14;22(10):2993–3005. doi: 10.3748/wjg.v22.i10.2993

Table 4.

Kaplan meier univariate analysis of overall accumulative survival in 316 hepatocellular carcinoma patients after radiofrequency ablation

Variable No. of patients Survival rate (%)
P value
1-yr 3-yr 5-yr 7-yr 10-yr
Sex 0.570
Male 250 89.8 70.4 53.2 44.8 33.0
Female 66 90.7 72.1 37.8 23.6 -
Age (yr) 0.163
< 60 176 90.3 67.6 48.0 31.7 26.4
≥ 60 140 89.6 75.8 58.0 55.4 25.2
Pathology grade < 0.001
Well-Moderate differentiated 126 94.4 82.5 64.2 53.0 42.5
Poor-differentiated 78 83.6 51.9 33.1 26.5 16.1
Etiology of cirrhosis 0.474
HBV 231 91.2 72.8 55.1 36.1 21.7
HCV 37 95.8 76.7 57.5 57.5 -
Portal vein hypertension < 0.001
No 211 94.2 78.5 63.0 51.8 36.2
Yes 103 79.8 53.2 30.2 20.4 10.2
Liver function enzyme 0.489
Normal 229 89.0 73.5 54.4 42.1 30.0
Elevated 87 92.2 64.1 45.6 40.5 -
Child-Pugh classification < 0.001
A 250 94.1 78.9 60.1 50.5 33.6
B 57 82.5 46.8 25.9 17.2 17.2
C 9 28.6 14.3 0 0 0
Serum AFP (ng/mL) 0.037
Normal 177 88.4 75.1 59.2 53.3 35.4
Abnormal 139 91.8 66 42.1 25.7 22.1
CEUS pre-RFA < 0.001
No 83 80.1 56.2 37.7 26.1 18.0
Yes 233 93.8 77.1 59.7 54.4 -
Number of tumors < 0.001
Single 248 90.6 75.3 59.3 46.8 34.5
≥ 2 68 87.6 54.6 27.0 21.6 10.8
Tumor size (cm) 0.178
≤ 3.0 147 94.0 71.6 59.2 49.0 18.4
3.0-5.0 169 86.8 69.8 47.3 36.4 25.2
Risky location 0.668
No 152 91.4 71.5 48.6 41.6 32.7
Yes 164 88.6 70.0 53.1 40.6 27.7
Type of RFA electrodes <0.001
Umbrella 213 86.8 64.3 45.7 36.7 23.6
Single 103 97.5 94.1 62.7 62.7 -
Primary technical success 0.006
Yes 301 89.9 69.1 51.4 39.6 30.6
No 15 54.5 36.4 18.2 0 0
Number of RFA sessions 0.793
1 256 90.2 70.1 53.4 40.3 31.0
≥ 2 60 89.3 73.4 49.0 42.4 30.3