Table 3: Effect and side effects of antiglaucoma medications in PCG patients
Class | Effect | Side effect | Nota bene | ||||
Beta blockers | Fair, no effect in 39-54% of patients | Possibility of apnea | To exclude asthma/cardiac anomaly before use. Check availability of 0.25% timolol, which is preferable in children | ||||
Carbonic anhydrase inhibitors | Fair | Growth suppression, metabolic acidosis | ― | ||||
Prostaglandin analogs | Poor, no effect in 50-80% of patients | Mainly local side effects as observed in adults | Predictors of poor response include severity glaucoma and young age of presentation | ||||
Alpha-2 agonists | ― | CNS suppression | Contraindicated in children | ||||
Parasympathomimetics | Poor | ― | Limited use in pediatric patient |