Table 3.
Antibiotic MIC Range, MIC50, and MIC90 (μg/mL) of Endophthalmitis Isolates
| Organism | Number | Drug | Range | MIC50 | MIC90 |
|---|---|---|---|---|---|
| Methicillin-resistant Staphylococcus aureus | 10 | Tigecycline | 0.25 to 0.5 | 0.5 | 0.5 |
| Azithromycin | >32.0 to >32.0 | >32.0 | >32.0 | ||
| Besifloxacin | 0.5 to 2.0 | 1.0 | 2.0 | ||
| Gatifloxacin | 2.0 to >32.0 | 4.0 | 32.0 | ||
| Moxifloxacin | 2.0 to 16.0 | 4.0 | 16.0 | ||
| Ciprofloxacin | 8.0 to >32.0 | >32.0 | >32.0 | ||
| Tobramycin | 0.5 to >32.0 | >32.0 | >32.0 | ||
| Methicillin-susceptible Staphylococcus aureus | 10 | Tigecycline | 0.125 to 8.0 | 0.125 | 0.5 |
| Azithromycin | 1.0 to >32.0 | >32.0 | >32.0 | ||
| Besifloxacin | 0.06 to 8.0 | 0.5 | 1.0 | ||
| Gatifloxacin | 0.125 to 8.0 | 2.0 | 8.0 | ||
| Moxifloxacin | 0.06 to 16.0 | 2.0 | 8.0 | ||
| Ciprofloxacin | 0.5 to >32.0 | 8.0 | >32.0 | ||
| Tobramycin | 0.5 to >32.0 | >32.0 | >32.0 | ||
| Methicillin-resistant coagulase-negative Staphylococcus | 10 | Tigecycline | 0.125 to 0.25 | 0.25 | 0.25 |
| Azithromycin | 0.5 to >32.0 | 0.5 | >32.0 | ||
| Besifloxacin | 0.06 to 8.0 | 0.5 | 8.0 | ||
| Gatifloxacin | 0.125 to >32.0 | 2.0 | >32.0 | ||
| Moxifloxacin | 0.125 to >32.0 | 2.0 | 32.0 | ||
| Ciprofloxacin | 0.25 to >32.0 | >32.0 | >32.0 | ||
| Tobramycin | 0.06 to >32.0 | 0.06 | 0.125 | ||
| Methicillin-susceptible coagulase-negative Staphylococcus | 10 | Tigecycline | 0.125 to 0.5 | 0.25 | 0.5 |
| Azithromycin | 0.25 to >32.0 | 16.0 | >32.0 | ||
| Besifloxacin | <0.03 to 4.0 | 0.25 | 4.0 | ||
| Gatifloxacin | 0.125 to >32.0 | 0.25 | >32.0 | ||
| Moxifloxacin | 0.06 to 32.0 | 0.06 | 16 | ||
| Ciprofloxacin | 0.125 to >32.0 | 8.0 | >32.0 | ||
| Tobramycin | 0.06 to 16.0 | 0.25 | 16.0 |