Table 2. Regression coefficients of presence and number of metabolic syndrome for elderly patients with total disability*.
| Variables | Model 1 | Model 2 | Model 3 | Model 4 | Model 5 | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| β (95% CI) | P value | β (95% CI) | Pvalue | β (95% CI) | P value | β (95% CI) | P value | β (95% CI) | P value | |
| Presence of metabolic syndrome | 0.366 (0.170, 0.562) | <0.001 | 0.306 (0.109, 0.503) | 0.002 | 0.283 (0.085, 0.480) | 0.005 | 0.219 (0.012, 0.426) | 0.038 | 0.216 (0.011,0.422) | 0.039 |
| Number of metabolic syndrome components | ||||||||||
| 1 | 0.073 (−0.315, 0.460) | 0.712 | 0.021 (−0.364, 0.406) | 0.915 | −0.007 (−0.391, 0.377) | 0.973 | 0.077 (−0.309, 0.463) | 0.696 | 0.058 (−0.325,0.441) | 0.767 |
| 2 | 0.362 (−0.010, 0.734) | 0.057 | 0.328 (−0.041, 0.698) | 0.082 | 0.29 (−0.079, 0.658) | 0.124 | 0.351 (−0.026, 0.729) | 0.068 | 0.327 (−0.048,0.702) | 0.087 |
| 3 | 0.446 (0.063, 0.829) | 0.022 | 0.359 (−0.023, 0.741) | 0.065 | 0.322 (−0.060, 0.703) | 0.098 | 0.380 (−0.017, 0.776) | 0.060 | 0.362 (−0.031,0.755) | 0.071 |
| 4 | 0.591 (0.184, 0.999) | 0.004 | 0.503 (0.096, 0.909) | 0.016 | 0.44 (0.032, 0.848) | 0.034 | 0.421 (−0.007, 0.849) | 0.054 | 0.411 (−0.014,0.835) | 0.058 |
| 5 | 0.875 (0.346, 1.404) | 0.001 | 0.739 (0.211, 1.267) | 0.006 | 0.681 (0.154, 1.208) | 0.011 | 0.632 (0.079, 1.186) | 0.025 | 0.573 (0.024,1.123) | 0.041 |
| P for trend | <0.001 | <0.001 | <0.001 | 0.002 | 0.002 | |||||
| Components of metabolic syndrome | ||||||||||
| Abdominal obesity | 0.495 (0.293, 0.697) | <0.001 | 0.458 (0.251, 0.664) | <0.001 | 0.446 (0.240, 0.651) | <0.001 | 0.451 (0.243, 0.658) | <0.001 | 0.447 (0.241,0.653) | <0.001 |
| High blood pressure | 0.002 (−0.147, 0.151) | 0.977 | −0.039 (−0.187, 0.110) | 0.610 | −0.044 (−0.192, 0.105) | 0.564 | −0.05 (−0.218, 0.119) | 0.563 | −0.08 (−0.248,0.087) | 0.348 |
| High triglycerides | 0.413 (0.208, 0.618) | <0.001 | 0. 38 (0.175, 0.585) | <0.001 | 0.385 (0.177, 0.593) | <0.001 | 0.317 (0.108,0.526) | 0.003 | 0.36 (0.153, 0.567) | 0.001 |
| Low HDL−cholesterol | 0.301 (0.089, 0.514) | 0.005 | 0.285 (0.073, 0.497) | 0.008 | 0.231 (0.018, 0.443) | 0.034 | 0.17 (−0.042,0.381) | 0.115 | 0.163 (−0.047, 0.372) | 0.128 |
| High glucose | 0.3 (0.092, 0.508) | 0.005 | 0.313 (0.106, 0.520) | 0.003 | 0.265 (0.058, 0.472) | 0.012 | 0.112 (−0.111,0.335) | 0.324 | 0.074 (−0.148, 0.295) | 0.513 |
Model 1 = unadjusted Model 2 = Model 1 + age, gender, and race−ethnicity Model 3 = Model 2 + (serum AST, serum total cholesterol, and serum total bilirubin) Model 4 = Model 3 + (smoking, hypertension, type 2 diabetes mellitus, and stroke) Model 5 = Model 4 + (Cognition impairment#).
#Cognition impairment was defined as the lowest quartile of DSST score.
*Total disability was defined as any difficulty in performing one or more activities within a given domain and assessed as the sum of five major domains at baseline and analyzed as a continuous variable.