. 2016 Mar 7;6:22374. doi: 10.1038/srep22374

Table 4. Arteriolopathy after CsA treatment for 7 weeks.

Treatment groups	N	Grade of arteriolopathy due to CsA nephrotoxicity	No. of positive cases	P value
VH^a	6	Absent to mild	6	< 0.01^a
VH^a	6	Moderate to severe	0
CsA^a,*	8	Absent to mild	0
CsA^a,*	8	Moderate to severe	8
CsA + M	6	Absent to mild	0
CsA + M	6	Moderate to severe	6
CsA + L(100mg/L) + M*	4	Absent to mild	2	< 0.05*
CsA + L(100mg/L) + M*	4	Moderate to severe	2	< 0.05*

N; number of subjects, VH; vehicle (olive oil), M; mizoribine, L; losartan.

CsA; cyclosporine A, Score of arteriolopathy due to chronic CsA toxicity (0: none, 1: rare and non-circumferential, 2: frequent and non-circumferential, 3: circumferential).