Table 2.
Combination Index | |||||
---|---|---|---|---|---|
Constant Ratio | |||||
Treatment | ED50 | ED75 | ED90 | ED95 | Dm |
Erl+GLE | 0.60914 | 0.54950 | 0.49573 | 0.46221 | 0.10815 |
Erl (μM) | 0.59348 | ||||
GLE (mg/mL) | 0.17742 | ||||
Non-constant Ratio | |||||
Dose Erl (μM) | Dose GLE (mg/mL) | Effect | CI | Description | |
0.06 | 0.05 | 0.23473 | 1.99448 | A | |
0.13 | 0.43761 | 0.64429 | S | ||
0.25 | 0.48714 | 0.76154 | MS | ||
0.50 | 0.52588 | 0.94897 | SlS | ||
1.00 | 0.57428 | 1.18357 | SlA | ||
2.00 | 0.65307 | 1.21960 | MA | ||
4.00 | 0.67108 | 2.00307 | A |
Dm means the median effect dose or the potency of each drug such as IC50, ED50. A=Antagonism, MA=Moderate Antagonism, MS=Moderate Synergism, S=Synergism, SlA=Slight Antagonism, SlS=Slight Synergism.