Table 1.
Demographics for healthy control and Parkinson’s disease participants
| HC | PD ALL | PD no-MCI | PD-MCI | PDD | p | |
|---|---|---|---|---|---|---|
| N | 22 | 64 | 28 | 22 | 14 | |
| Male/Female | 8/14 | 35/29 | 13/15 | 14/8 | 8/6 | |
| Age (years)^ | 65.10 ± 6.89 | 68.36 ± 7.91 | 65.11 ± 7.21 | 69.14 ± 7.98 | 73.21 ± 6.68 | * # |
| Education (years)^ | 16.81 ± 2.03 | 16.44 ± 2.42 | 16.48 ± 2.36 | 16.41 ± 2.56 | 16.71 ± 2.16 | NS |
| Duration (years)^ | n/a | 5.92 ± 4.18 | 5.04 ± 3.47 | 6.64 ± 4.82 | 6.57 ± 4.38 | NS |
| MDS-UPDRS III (OFF)^ | n/a | 37.47 ± 10.94 | 35.79 ± 10.53 | 34.00 ± 9.40 | 46.79 ± 9.37 | # % |
| MDS-UPDRS III (ON)^ | n/a | 21.54 ± 11.11 | 19.81 ± 9.62 | 18.89 ± 10.32 | 29.85 ± 11.67 | # % |
| LEDD^ | n/a | 695.4 ± 366.1 | 657.8 ± 382.7 | 831.8 ± 325.8 | 556.2 ± 344.1 | NS |
| BDI^ | 3.64 ± 3.88 | 11.13 ± 8.34 | 9.26 ± 7.58 | 11.09 ± 7.08 | 13.92 ± 11.39 | ** |
| BAI^ | 2.68 ± 2.85 | 11.09 ± 8.80 | 11.43 ± 9.00 | 11.32 ± 8.34 | 10.04 ± 9.63 | ** |
PD Parkinson’s disease, PDD PD with Dementia, PD-MCI PD with mild cognitive impairment, PD no-MCI PD with no cognitive impairment, HC healthy controls, MDS-UPDRS III Movement Disorders Society-Unified Parkinson’s disease Rating Scale, motor scale, LEDD levodopa equivalent daily dose, BDI Beck’s Depression Inventory, BAI Beck’s Anxiety Inventory
^ = mean ± standard deviation; * = p < .05 PDD vs HC; # = p < .05 PDD vs PD no-MCI; % = p < .05 PDD vs PD-MCI; ** = p < 0.05 HC vs All PD groups; NS = not significant