Table 3. P2 residues from genomes of six human CoVs.

No.	Cleavage Site	Alphacoronavirus		Betacoronavirus
		HCoV-NL63	HCoV-229E	HCoV-HKU1	HCoV-OC43	SARS-CoV	MERS-CoV
1	nsp4-nsp5	L	L	L	L	L	L
2	nsp5-nsp6	L	L	L	L	F	M
3	nsp6-nsp7	V	V	I	F	V	M
4	nsp7-nsp8	L	L	L	L	L	L
5	nsp8-nsp9	L	L	M	L	L	L
6	nsp9-nsp10	L	L	L	L	L	L
7	nsp10-nsp11	I	I	V	V	M	P
8	nsp12-nsp13	L	L	M	M	L	L
9	nsp13-nsp14	L	L	L	V	L	L
10	nsp14-nsp15	L	L	L	L	L	V
11	nsp15-nsp16	L	L	M	L	L	L