Table 11.
Liver weights of male F344 rats from a 2-year feeding study of p,p′-DDT
| Dose (ppm) | Liver weights | Weeks on study | |||
|---|---|---|---|---|---|
|
| |||||
| 26 | 52 | 78 | 104 | ||
| 5 | Absolute | 106 (6) | 108 (6) | 108 (8) | 110 (10) |
| Relative | 102 (6) | 108 (6) | 105 (8) | 105 (10) | |
| 50 | Absolute | 114 (6)** | 117 (6)* | 126 (8)** | 125 (10)** |
| Relative | 112 (6)* | 118 (6)* | 125 (8)** | 123 (10)* | |
| 500 | Absolute | 166 (6)** | 154 (6)** | 153 (7)** | 149 (10)** |
| Relative | 170 (6)** | 168 (6)** | 166 (7)** | 171 (10)** | |
Values represent percentages (%) to control values.
(n): Number of animals examined.
Relative: Ratio to body weight (%)
*, **
Significantly different from control at p < 0.05 and p < 0.01, respectively (Dunnett’s multiple comparison test).