TABLE 2.
Associations between cannabis exposure and respiratory symptoms at age 38 years
Cannabis use | Participants n | OR (95% CI) | p-value | |
---|---|---|---|---|
Cough | Current | 942 | 3.46 (2.02–5.93) | <0.001 |
Cumulative | 934 | 1.07 (1.03–1.10) | <0.001 | |
Cumulative (excluding current frequent users) | 839 | 1.07 (1.00–1.15) | 0.047 | |
Sputum | Current | 942 | 3.45 (1.96–6.11) | <0.001 |
Cumulative | 934 | 1.04 (1.01–1.08) | 0.017 | |
Cumulative (excluding current frequent users) | 839 | 0.92 (0.81–1.05) | 0.220 | |
Wheeze | Current | 943 | 1.95 (1.11–3.42) | 0.020 |
Cumulative | 935 | 1.05 (1.02–1.09) | 0.002 | |
Cumulative (excluding current frequent users) | 840 | 1.09 (1.02–1.17) | 0.008 | |
Dyspnoea | Current | 941 | 1.73 (1.00–2.99) | 0.048 |
Cumulative | 933 | 1.04 (1.00–1.07) | 0.031 | |
Cumulative (excluding current frequent users) | 838 | 1.04 (0.98–1.12) | 0.214 |
Analyses are adjusted for current and cumulative (pack-years) tobacco smoking, sex, body mass index, and asthma diagnosis. Odds ratios represent the odds associated with current frequent cannabis use compared to non- or infrequent use or with each additional joint-year of cumulative lifetime exposure. Differences between n-values for current and cumulative use reflect missing data.