Table 1.
Demographic, lifestyle, and reproductive history of Effects of Aspirin in Gestation and Reproduction study population by inter-trying interval (ITI)*
| Inter-trying interval | ||||
|---|---|---|---|---|
| Characteristics | Total n=998 |
0–3mo n=765 (76.7) |
>3mo n=233 (23.4) |
P-value1 |
| Age, years (mean ± SD) | 28.8 ± 4.8 | 28.6 ± 4.8 | 29.4 ± 4.8 | 0.02 |
| Partner age, years (mean ± SD) | 30.1 ± 5.4 | 29.8 ± 5.3 | 31.0 ± 5.7 | 0.01 |
| BMI, kg/m2 (mean ± SD) | 26.2 ± 6.5 | 26.0 ± 6.4 | 27.2 ± 7.0 | 0.01 |
| Race | 0.001 | |||
| White | 955 (95.7) | 741 (96.9) | 214 (91.9) | |
| Non-White | 43 (4.3) | 24 (3.1) | 19 (8.2) | |
| Education | <0.001 | |||
| > High School | 871 (87.2) | 683 (89.2) | 188 (80.7) | |
| ≤ High School | 126 (12.6) | 81 (10.6) | 45 (19.3) | |
| Low-dose aspirin Treatment | 499 (50.0) | 388 (50.7) | 111 (47.6) | 0.42 |
| Smoking in past year | 0.003 | |||
| No | 952 (95.4) | 738 (96.5) | 214 (91.9) | |
| Yes | 46 (4.6) | 27 (3.5) | 19 (8.2) | |
| Alcohol consumption in past year | 0.05 | |||
| Never | 656 (65.7) | 516 (67.4) | 140 (60.1) | |
| Sometimes | 313 (31.3) | 237 (31.0) | 86 (36.9) | |
| Often | 21 (2.1) | 14 (1.8) | 7 (3.0) | |
| Coffee consumer | 272 (27.3) | 201 (26.3) | 71 (30.5) | 0.20 |
| Physical Activity | 0.91 | |||
| Low | 251 (25.2) | 190 (24.8) | 61 (26.2) | |
| Moderate | 419 (42.0) | 322 (42.1) | 97 (41.6) | |
| High | 328 (32.9) | 253 (33.1) | 75 (32.2) | |
| Income | 0.77 | |||
| ≥$100 000 | 393 (39.4) | 293 (38.3) | 100 (42.9) | |
| $75 000-99 999 | 123 (12.3) | 96 (12.6) | 27 (11.6) | |
| $40 000-74 999 | 152 (15.2) | 117 (15.3) | 35 (15.0) | |
| $20 000-39 999 | 255 (25.6) | 211 (26.3) | 54 (23.2) | |
| ≤$19 999 | 75 (7.5) | 58 (7.6) | 17 (7.3) | |
| Marital Status | 0.03 | |||
| Married | 917 (91.9) | 712 (93.1) | 205 (87.9) | |
| Living with a partner | 57 (5.7) | 39 (5.1) | 18 (7.7) | |
| Other | 24 (2.4) | 14 (1.8) | 10 (4.3) | |
| Previous subfertility | 74 (7.4) | 50 (6.5) | 24 (10.3) | 0.05 |
| Age of Menarche (years) | 12.7 ± 1.5 | 12.5 ± 1.5 | 12.8 ± 1.5 | 0.01 |
| Ever Hormonal Prescriptions | 796 (79.8) | 602 (78.7) | 194 (83.4) | 0.12 |
| Previous Number of Live Births | 0.59 | |||
| 0 | 498 (49.9) | 376 (49.2) | 122 (52.4) | |
| 1 | 345 (34.6) | 266 (34.8) | 79 (33.9) | |
| 2 | 155 (15.5) | 123 (16.1) | 32 (13.7) | |
| Previous Number of Losses | 0.10 | |||
| 1 | 669 (67.0) | 523 (68.4) | 146 (62.7) | |
| 2 | 329 (33.0) | 242 (31.6) | 87 (37.3) | |
| D & C performed on prior loss | 324 (32.5) | 250 (32.7) | 74 (31.8) | 0.79 |
| Gestational age of prior loss (weeks) | 0.01 | |||
| ≤7.99 | 439 (44.0) | 336 (43.9) | 101 (43.3) | |
| 8-13.99 | 503 (50.4) | 397 (51.9) | 106 (45.5) | |
| 14-19.99 | 52 (5.2) | 30 (3.9) | 22 (9.4) | |
| 20-31.99 | 3 (0.003) | 2 (0.3) | 1 (0.004) | |
| Age of first intercourse (years) | 19.5 ± 4.2 | 19.8 ± 4.3 | 18.6 ± 3.8 | <0.001 |
| Past month’s intercourse frequency | 0.88 | |||
| ≥3-6 per week | 315 (31.5) | 242 (31.6) | 72 (30.9) | |
| 1-2 per week to 2-3 per month | 579 (58.0) | 439 (57.4) | 140 (60.1) | |
| <1 per month | 54 (5.4) | 42 (5.5) | 12 (5.2) | |
Analyses performed via chi-square or Fisher’s exact test as appropriate for categorical variables and Student’s t test for continuous variables. Values reported are n (%) unless otherwise noted. All variables are complete except for missing n=85 for ITI (i.e., did not complete question on how long they had currently been trying to conceive or did not have a documented date of last loss), n=1 for partner age, n=1 for education, n=8 for past year’s alcohol consumption, n=4 for previous subfertility report, n=11 for age of menarche, n=1 for gestational age of prior loss, n=2 for age of first intercourse, and