Table 4.
Fecundability odds ratio (FOR) for pregnancy and pregnancy leading to a live birth (95% CI) by inter-trying interval (0–3 months versus > 3 months) stratified by LDA treatment
| LDA Treatment | ||||
|
| ||||
| Time to Pregnancy | FOR (95% CI) | |||
|
| ||||
| Inter-trying interval |
Pregnancy
n (%) |
Unadjusted |
Adjusted
Model 1* |
Adjusted
Model 2† |
|
| ||||
| 0–3 months | 278 (71.7) | 1.65 (1.21, 2.26) | 1.50 (1.09, 2.06) | 1.46 (1.06, 2.02) |
| >3 months | 61 (55.0) | 1.0 | 1.0 | 1.0 |
|
| ||||
| Time to Pregnancy Leading to a Live Birth | FOR (95% CI) | |||
|
| ||||
| Inter-trying interval |
Pregnancy
n (%) |
Unadjusted |
Adjusted
Model 1* |
Adjusted
Model 2† |
|
| ||||
| 0–3 months | 216 (55.7) | 1.69 (1.18, 2.41) | 1.52 (1.06, 2.18) | 1.50 (1.04, 2.16) |
| >3 months | 46 (41.4) | 1.0 | 1.0 | 1.0 |
|
| ||||
| Placebo | ||||
|
| ||||
| Time to Pregnancy | FOR (95% CI) | |||
|
| ||||
| Inter-trying interval | Pregnancy n (%) | Unadjusted |
Adjusted
Model 1* |
Adjusted
Model 2† |
|
| ||||
| 0–3 months | 247 (65.5) | 1.70 (1.22, 2.35) | 1.60 (1.14, 2.24) | 1.54 (1.10, 2.16) |
| >3 months | 58 (47.5) | 1.0 | 1.0 | 1.0 |
|
| ||||
| Time to Pregnancy Leading to a Live Birth | FOR (95% CI) | |||
|
| ||||
| Inter-trying interval |
Pregnancy
n (%) |
Unadjusted |
Adjusted
Model 1* |
Adjusted
Model 2† |
|
| ||||
| 0–3 months | 191 (50.7) | 1.98 (1.34, 2.93) | 1.86 (1.24, 2.78) | 1.83 (1.21, 2.77) |
| >3 months | 38 (31.2) | 1.0 | 1.0 | 1.0 |
*
Adjused for age, race, BMI, education, and subfertility.
†
Adjusted for Model 1 covariates plus partner’s age, smoking, alcohol intake, parity, previous number of losses, recency of loss, gestational age of last loss, age of first intercourse, age of menarche, and D & C performed for last loss.