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Functional and chromosome copy number analyses in Class 1 primary uveal melanoma. (A) Gene Set Enrichment Analysis (GSEA) of annotated gene sets exhibiting significant enrichment for genes that were up-regulated in Class1PRAME+ tumors relative to Class1PRAME− tumors. (B) High density Affymetrix Genome-Wide Human SNP 6.0 Array analysis of Class1PRAME+ and Class1PRAME− tumors with respect to metastatic status. Blue indicates copy number loss, and red, copy number gain.
