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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Clin Immunol. 2016 Jan 28;164:85–94. doi: 10.1016/j.clim.2016.01.015

Figure 3. FLS is decreased in salivary tissue as a result of BAFF receptor blockade.

Figure 3

Histological analysis of H&E stained salivary tissue from NOD/ShiltJ mice treated with (A) I.C. (n = 10), (B) BAFFR-Fc (n = 9), and (C) Anti-CXCL13/BAFFR-Fc (n = 9). White arrows indicate lymphocytic foci. (D) Quantification of histological data shown in graph. Red shapes indicate animals selected for further analysis in Figure 4. I.C. = isotype control. Significance was determined using the Mann-Whitney test. Mean and SEM are shown (**p < 0.01, ***p < 0.001, N.S. non-significant). Original magnification is 40X.