TABLE I.
Characteristics of 352 External Genital Lesions* That Underwent Pathological Evaluation
| n (%) | |
|---|---|
| Country | |
| USA | 112 (31.8%) |
| Brazil | 137 (38.9%) |
| Mexico | 103 (29.3%) |
| Age (years) | |
| Range | 20–66 |
| Median (IQR) | 31 (25–39) |
| 18–30 | 173 (49.2%) |
| 31–44 | 141 (40.1%) |
| 45+ | 38 (10.8%) |
| Anatomical site | |
| Coronal sulcus | 37 (10.5%) |
| Glans, including meatus | 14 (4.0%) |
| Inguinal | 12 (3.4%) |
| Mons | 3 (0.9%) |
| Penile shaft | 215 (61.1%) |
| Perianal | 29 (8.2%) |
| Perineum | 1 (0.3%) |
| Scrotum | 41 (11.7%) |
| Pathological diagnosis—Pathologist #1 | |
| Not condyloma/HPV | 83 (23.6%) |
| Suggestive but not diagnostic of HPV | 112 (31.8%) |
| Condyloma | 145 (41.2%) |
| Penile intraepithelial neoplasia, grade I | 2 (0.6%) |
| Penile intraepithelial neoplasia, grades II/III | 10 (2.8%) |
| HPV genotyping (INNO-LiPA) | |
| Positive | 294 (83.5%) |
| Negative | 40 (11.4%) |
| Invalid | 18 (5.1%) |
| Rounded papillomatisis | |
| Yes | 128 (76.7%) |
| No | 39 (23.3%) |
| Parakeratosis | |
| Yes | 93 (55.7%) |
| No | 74 (44.3%) |
| Hypergranulosis | |
| Yes | 104 (62.3%) |
| No | 63 (37.7% |
| Koilocytes | |
| Yes | 37 (22.2%) |
| No | 130 (77.8%) |
| Dilated vessels | |
| Yes | 106 (63.5%) |
| No | 61 (36.5%) |
| Binucleation | |
| Yes | 10 (6.0%) |
| No | 157 (94.0%) |
| Horn cysts | |
| Yes | 8 (4.8%) |
| No | 159 (95.2%) |
| Hyperpigmentation | |
| Yes | 18 (10.8%) |
| No | 149 (89.2%) |
| Dysplasia/atypia | |
| Yes | 8 (4.9%) |
| No | 157 (95.1%) |
*
Multiple lesions were possible for each man.