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. 2015 Sep 9;10(2):288–294. doi: 10.5009/gnl14368

Fig. 1.

Fig. 1

Increased frequencies of programmed death 1 (PD-1)+ or cytotoxic T lymphocyte antigen 4 (CTLA-4)+ T-cells from patients with symptomatic acute hepatitis A (AHA) compared to nonviral acute toxic hepatitis (ATH). (A) %PD-1+ (median: ATH, 3.6; AHA, 18.3; healthy, 1.6), %PD-1+/CD8, and %PD-1+/CD4 T-cells from six patients with nonviral ATH, seven patients with AHA, and five healthy controls. (B) %CTLA-4+ (median: ATH, 6.8; AHA, 23.5; healthy, 5.9), %CTLA-4+/CD8, and %CTLA-4+/CD4 T-cells from patients with nonviral ATH, AHA, and in healthy controls. *p-values by Kruskal-Wallis; †p-values by Mann-Whitney U test.