Fig. 2.

(A) Dot plot (upper) and histogram (lower) of flow cytometry. (B) Graphic representaion of the flow cytometry data. Simvastatin suppresses cell proliferation via the induction of G1 phase cell cycle arrest in bile duct cancer cells. Cell cycle analysis by flow cytometry was performed using bile duct cancer cells after 48 or 72 hours of treatment with 50 μM simvastatin. These results represent three separate experiments.

SV, simvastatin 50 μM. *p<0.05 vs untreated control; ^†p<0.05 vs untreated control and 48 hours of treatment.