Table 2.
Comparison of 3 different classes of intraoperative adjunctive medications for glaucoma surgery.
Main Indication | Advantages | Disadvantages | |
---|---|---|---|
Sub-Tenon Steroids | Primary trabeculectomy | Are available and inexpensive Reduce postoperative inflammation | May induce IOP rise in steroid-responders May not be as effective as anti-fibrotics |
Anti-Fibrotics | High-Risk patients Imminent failure | Very effective | Associated with thin bleb and bleb-related complications |
Anti-VEGF Agents | Neovascular glaucoma Primary trabeculectomy | Maximum ocular safety Reduce postoperative hyphema and inflammation | May induce systemic vascular attacks in susceptible patients May promote avascular blebs |