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. 2016 Feb 29;10:68–85. doi: 10.2174/1874364101610010068

Table 2.

Comparison of 3 different classes of intraoperative adjunctive medications for glaucoma surgery.

Main Indication Advantages Disadvantages
Sub-Tenon Steroids Primary trabeculectomy Are available and inexpensive Reduce postoperative inflammation May induce IOP rise in steroid-responders May not be as effective as anti-fibrotics
Anti-Fibrotics High-Risk patients Imminent failure Very effective Associated with thin bleb and bleb-related complications
Anti-VEGF Agents Neovascular glaucoma Primary trabeculectomy Maximum ocular safety Reduce postoperative hyphema and inflammation May induce systemic vascular attacks in susceptible patients May promote avascular blebs