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. 2016 Feb 16;113(9):2484–2489. doi: 10.1073/pnas.1518934113

Table S2.

Full list of HCV-associated cellular proteins identified by MS

No. Identifier Gene name Protein name Log(e) No. of MS/MS spectra Molecular mass, kDa Gel slice
1 ENSP00000351416 ANKRD17 Ankyrin repeat domain 17 −54.9 9 274.1 A
2 ENSP00000448366 SCYL2 SCY1-like 2 −18.1 3 77 A
3 ENSP00000392423 RELN Reelin −7.9 3 388.1 A
4 ENSP00000451870 TRAJ56 T-cell receptor alpha joining 56 −2.5 2 2.2 A
5 ENSP00000376899 PTGFRN Prostaglandin F2 receptor inhibitor −54.3 12 98.5 B
6 ENSP00000295598 ATP1A1 ATPase, Na+/K+ transporting, alpha-1 polypeptide −27.4 5 112.8 B
7 ENSP00000316032 NUP98 Nucleoporin 98kDa −17.3 6 195.7 B
8 ENSP00000438588 MTHFD1 Methylenetetrahydrofolate dehydrogenase (NADP+-dependent) 1 −13.5 4 110.5 B
9 ENSP00000261973 RBM25 RNA binding motif protein 25 −10.2 3 100.1 B
10 ENSP00000421907 ADD1 Adducin 1 (alpha) −8.2 3 70 B
11 ENSP00000415559 EGFR Epidermal growth factor receptor −6.1 3 120.6 B
12 ENSP00000367122 SLC3A2 Solute carrier family 3, member 2 −23.8 4 68 C
13 ENSP00000264883 NUP54 Nucleoporin 54kDa −14.3 6 55.4 C
14 ENSP00000316664 IGSF8 Ig superfamily, member 8 −8.5 2 65 C
15 ENSP00000441751 JUP Junction plakoglobin −8.3 5 66.3 C
16 ENSP00000388491 CNOT4 CCR4-NOT transcription complex, subunit 4 −8.2 2 77.8 C
17 ENSP00000387282 AGFG1 ArfGAP with FG repeats 1 −7.7 3 60.7 C
18 ENSP00000321347 STRBP Spermatid perinuclear RNA binding protein −4.9 2 73.6 C
19 ENSP00000355890 EPRS Glutamyl-prolyl-tRNA synthetase −4 2 170.5 C
20 ENSP00000368884 RPS6KA3 Ribosomal protein S6 kinase alpha-3 −3.1 3 83.7 C
21 ENSP00000424874 PGM3 Phosphoglucomutase-3 −2.6 2 59.8 C
22 ENSP00000233078 DAZAP1 DAZ-associated protein 1 −8.2 2 43.4 D/F
23 ENSP00000286713 STOM Stomatin −28 3 31.7 E
24 ENSP00000260130 SDCBP Syndecan binding protein (syntenin) −10.7 3 32.4 E
25 ENSP00000221566 SGTA Small glutamine-rich tetratricopeptide repeat-containing, alpha −10.3 3 34 E
26 ENSP00000300161 YWHAB Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta-polypeptide −6.7 2 28.1 E
27 ENSP00000383981 RPS27A Ribosomal protein S27a −4.4 4 18 E
28 ENSP00000342026 PRDX6 Peroxiredoxin 6 −3.9 2 25 E
29 ENSP00000447938 CD63 CD63 molecule −3.9 2 16 E
30 ENSP00000227525 TMEM109 Transmembrane protein 109 −35.2 15 26.2 G
31 ENSP00000278222 SAA4 Serum amyloid A4, constitutive −12.8 3 14.7 G
32 ENSP00000340761 BRI3BP BRI3 binding protein −11.9 3 27.8 G
33 ENSP00000307705 HIST1H1E Histone cluster 1, H1e −11 2 21.9 G
34 ENSP00000295522 CLDN1 Claudin 1 −10.1 3 22.7 G
35 ENSP00000263645 CD81 CD81 molecule −9.8 2 25.8 G
36 ENSP00000435096 RPS25 Ribosomal protein S25 −9.3 3 13.7 G
37 ENSP00000236671 CTSD Cathepsin D −8.7 2 44.5 G
38 ENSP00000322419 RPLP2 Ribosomal protein, large, P2 −7.6 3 11.7 G
39 ENSP00000400591 SNRPE Small nuclear ribonucleoprotein polypeptide E −7.3 2 10.8 G
40 ENSP00000257013 FAM127A Family with sequence similarity 127, member A −7.2 3 13.2 G
41 ENSP00000360399 TMEM59 Transmembrane protein 59 −6.9 2 21.8 G
42 ENSP00000325376 HNRNPM Heterogeneous nuclear ribonucleoprotein M −6.8 2 77.5 G
43 ENSP00000233596 REEP6 Receptor accessory protein 6 −6.4 2 20.7 G
44 ENSP00000309757 LPL Lipoprotein lipase −5.6 2 53.1 G
45 ENSP00000358089 TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 −4.8 2 43.4 G
46 ENSP00000261811 CYSTM1 Cys-rich transmembrane module containing 1 −4.8 2 10.6 G

ArfGAP, GTP-ase activating protein for ADP-ribosylation factors; BRI3, brain protein I3; CCR4-NOT, chemokine (C-C motif) receptor 4; DAZ, deleted in azoospermia; FG, phe-gly; TIA1, T-cell restricted intracellular antigen-1. In bold, candidate hits selected for follow-up studies.