Table S1.

General and dermatological features

Clinical features	Total	Mild XP-A*	%	XP-A	%	XP-B	%	XP-C	%	XP-D	%	XP-E	%	XP-F	%	XP-G	%	XP-V	%
Total cases reported	89	10	11	8	9	2	2	28	31	14	16	4	4	3	3	8	9	12	13
Men	38	6	60	4	50	0		14	50	7	50	0		2	67	4	50	7	58
Women	41	4	40	4	50	2	100	14	50	7	50	4	100	1	33	4	50	5	42
Median age as of December 2014 (y)		35		17		45		14		24		56		23		19		55
Median age at diagnosis (y)		32		8		36		5		4		47		9		8		44
Age at onset of cutaneous symptoms (y) (average)		4		0.4		1		3		0.6		17		1		0.6		27
Sunburn severity score (median)		1		3		3		0		3		1		3		3		0
Mean age at onset of lentigines stated (y)		3		7		3		3		8		15		15		6		15
Age photoprotection started (y) (average)		24		3		2		10		10		17		15		10		39
Presence of lentigines at exposed sites		10	100	7	88	2	100	28	100	10	7	4	100	1	33	6	75	12	100
Hypopigmented macules		7	70	3	38	2	100	24	86	10	71	4	100	0		5	63	7	58
Cutaneous atrophy/actinic damage present		1	10	0	0	2	100	7	25	9	64	3	75	0		0		11	92
Malignant skin neoplasms
Present		2	20	1	0	1	50	15	54	9	64	3	75	0		0		10	83
Absent
Age first skin cancer (y) (median)		38		8		22		11		14		15		NA		NA		36
Type of first cutaneous neoplasm
BCC		1						11		8		2		NA		NA		3
SCC				1				2		1				NA		NA		2
Melanoma/MIS		1				1		2				1		NA		NA		5

^*This is the group of XP-A with the c.555+8A > G mutation. NA, Not applicable.