Table 2.
Outcome of treatment with autologous serum in eyes with different types of ocular surface disease
| Indication | Patientsa, n (%) | Eyes, n (%) | Treatments, n | Proportion of eyes with > 1 treatment (%) | Duration of treatmentb, median (range) days | Proportion of eyes with healed epitheliumb, n (%) | Follow-upc, median (range) months |
|---|---|---|---|---|---|---|---|
| PED | 14 (58.3) | 16 (50.0) | 22 | 4 (25.0) | 15 (3–35) | Complete healing: 6 (37.5); partial success: 3 (18.8); 7 (43.8)d | 12.5 (2–88) |
| SPK | 5 (20.8) | 9 (28.1) | 9 | 0 (0) | 7 (5–21) | 3 (33.3) complete healing, 2 (22.2) partial success, 4 (44.4)d | 66 (<1–121) |
| Perforation | 5 (20.8) | 5 (15.6) | 5 | 0 (0) | 14.5 (6–23) | NA | 28 (<1–71) |
| Pain post-LASIK | 1 (4.2) | 2 (6.3) | 4 | 1 (100) | 217 (NA) | NA | 9 |
Notes:
a
N=24 patients. However, in one patient, one eye was classified as having PED and the other eye as with perforation, hence the sum of 25 patients.
b
Only first treatment included.
c
Follow-up time is given for all eyes (n=32).
d
Remaining 43.8% with no measurable effect, lost to follow-up, or suspected noncompliance.
Abbreviations: LASIK, laser-assisted in situ keratomileusis; NA, not applicable; PED, persistent epithelial defect; SPK, superficial punctate keratitis.